Plant Transcription Factor Database
Previous version: v3.0
Nicotiana tabacum
BES1 Family
Species TF ID Description
XP_016434229.1BES1 family protein
XP_016437198.1BES1 family protein
XP_016437199.1BES1 family protein
XP_016453047.1BES1 family protein
XP_016463430.1BES1 family protein
XP_016463704.1BES1 family protein
XP_016466051.1BES1 family protein
XP_016468029.1BES1 family protein
XP_016468030.1BES1 family protein
XP_016469209.1BES1 family protein
XP_016469210.1BES1 family protein
XP_016469211.1BES1 family protein
XP_016470141.1BES1 family protein
XP_016472541.1BES1 family protein
XP_016473761.1BES1 family protein
XP_016484151.1BES1 family protein
XP_016484152.1BES1 family protein
XP_016484153.1BES1 family protein
XP_016496061.1BES1 family protein
XP_016496062.1BES1 family protein
XP_016496466.1BES1 family protein
XP_016505654.1BES1 family protein
XP_016508570.1BES1 family protein
XP_016510533.1BES1 family protein
XP_016510539.1BES1 family protein
XP_016510545.1BES1 family protein
XP_016510553.1BES1 family protein
BES1 Family Introduction

Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J.
A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
Cell. 2005 Jan 28;120(2):249-59.
PMID: 15680330